Caryophyllene Oxide (also known as Caryophyllin or Epoxycaryophyllene) is a naturally occurring sesquiterpene oxide formed through the oxidation of β-caryophyllene. It is widely found in the essential oils of numerous plant species. At room temperature, it presents as a white crystalline powder, possessing a unique, complex aroma characterized by woody, spicy, and camphoraceous notes, accompanied by a subtle sweetness and an herbal undertone.
99% White crystalline powder or solid Caryophyllene Oxide
Product Characteristics:
Chemical Name: Trimethyl-9-methylene-5-oxatricyclo[8.2.0.0⁴,⁶]dodecane
CAS No.: 1139-30-6
FEMA No.: 3553 (GRAS)
Molecular Formula: C₁₅H₂₄O
Molecular Weight: 220.35
Melting Point: 55–63°C
Boiling Point: 279.7°C (approx. 279–301°C)
Density: 0.96–0.98 g/cm³
Appearance: White crystalline powder or solid
Aroma: A complex woody-spicy-camphoraceous scent, with sweet nuances and herbal undertones
Optical Rotation: [α]²⁰/D −70° (in chloroform)
Purity Specification: ≥95% to ≥99%
99% White crystalline powder or solid Caryophyllene Oxide
99% White crystalline powder or solid Caryophyllene Oxide
Applications:
Food Industry (Core Application):
Seasonings & Sauces: Imparts a complex woody-spicy-camphoraceous aroma; simulates natural flavors such as black pepper and clove
Baked Goods: Cookies, bread, pastries, etc.
Meat Products & Seafood: Masks fishy odors; adds smoky and spicy flavor notes
Beverages & Dairy Products: Tea drinks, coffee, plant-based beverages, dairy products
Snack Foods: Nuts, puffed snacks
Confectionery & Alcoholic Beverages: Hard candies, chewing gum, compounded alcoholic drinks
Recommended Usage in Food: As a fragrance component in the formulation of various flavorings, the recommended dosage is 2–200 mg/kg; as a natural flavor enhancer, an addition level of just 0.01% can provide a longer-lasting aftertaste in citrus-based beverages. 2. Daily Chemicals and Cosmetics:
Perfumes & Fragrances: Acts as a middle-to-base note fixative, enhancing aromatic complexity and stability while extending scent longevity.
Skincare: Creams, serums, shampoos, and hair conditioners; provides antioxidant benefits.
Oral Care: Toothpastes and mouthwashes.
Home Fragrance: Scented candles, laundry detergents, etc.
Other Applications:
Pesticides: Serves as a naturally derived insecticidal and insect-repellent ingredient.
Research Reagents: Used as an analytical standard reference material.
Pharmaceutical Sector:
Anti-inflammatory & Analgesic: Possesses demonstrated analgesic and anti-inflammatory activity.
Anti-cancer Activity: Exhibits anti-proliferative properties and acts as a chemotherapy sensitizer.
Antifungal: Inhibits the growth of various fungi; applicable in the treatment of onychomycosis (nail fungus).
Skin Penetration Enhancer: Facilitates the absorption of active ingredients through the skin.
Cardiovascular Protection: Exerts a relaxant effect in smooth muscle preparations, acting as a calcium channel blocker.
99% White crystalline powder or solid Caryophyllene Oxide
Core Functional Characteristics:
Excellent Thermal Stability:
Boiling point ranges from 279°C to 301°C, making it suitable for high-temperature processing applications (baking, frying, canning).
Its aromatic profile remains stable under high-temperature conditions, resisting decomposition and loss.
Fixation & Fragrance Enhancement:
Acts as a “binder” in multi-note fragrance formulations, compatible with a wide range of scent profiles including floral, woody, and fougère notes.
Enhances aromatic complexity and stability, significantly extending the duration of the scent.
Natural Preservative:
Effective inhibitory concentration against common microorganisms is as low as 0.5 mg/mL.
Causes significantly less irritation than traditional preservatives, aligning with the consumer trend toward “natural and additive-free” products.
Antioxidant Properties:
Scavenges free radicals, delaying lipid oxidation and flavor deterioration.
Extends product shelf life while maintaining stable color and sensory quality.
99% White crystalline powder or solid Caryophyllene Oxide
